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Growing up in a small town, Charlie, Alex and Nick weren't the most popular kids around after they formed "The Elite Monster Unit". Chasing notorious, mythical legends and ghosts was exciting to them, not "cool" to the other kids around. So they lived their lives on the outside of the "in" crowd. Making matters worse was Charlie's obvious crush on Brandy, one of the most popular kids in school and sister to one of the biggest bullies around. Trying to impress Brandy, Charlie accepts a dare from her brother Nick that says he and his friends must spend Halloween night in a house long rumored to be haunted.What seems to be an easy challenge quickly turns out to be a night of frights as Charlie, Nick and Alex find themselves in the fight of their lives trying to out smart (and outrun) their new nemesis, a ghost dog named Salty, who does whatever he can to make this the worst night of their lives...。一场可怕的车祸让克莱尔（詹妮弗·安妮斯顿 Jennifer Aniston 饰）不仅容貌尽毁，还失去了挚爱的儿子，之后，深陷于绝望和痛苦中无法自拔的克莱尔患上了慢性疼痛症。为了同疾病做斗争，克莱尔来到了慢性疼痛俱乐部，通过和病友们的相互交流与鼓励，获得生活下去的信心和希望。 妮娜（安娜·肯德里克 Anna Kendrick 饰）是俱乐部中的一员，某日，她自杀身亡的消息震惊了克莱尔。克莱尔想方设法寻求妮娜自杀的真相，最后甚至陷入了同妮娜对话的幻觉之中无法自拔，与此同时，妮娜的丈夫罗伊（萨姆·沃辛顿 Sam Worthington 饰）亦出现在了克莱尔的身旁，将克莱尔卷入了一个又一个漩涡之中。。