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五位多年未见的闺密，因为参加其中一人在加勒比海举行的海岛婚礼而再度聚首，闲暇之余，她们决定搭船前往一个无人岛探险，没想到该岛的周围潜藏着饥肠辘辘的鲨鱼，五人必须设法从鲨口逃生……。。FRAMING AGNES turns the talk show format inside out in response to media's ongoing fascination with trans people. The film breathes life into six previously unknown stories from the archives of the UCLA Gender Clinic in the 1950s.。